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Psychology Research Institute Psychology Research Institute

Prof. dr. E. (Eirini) Karyotaki PhD

Faculty of Social and Behavioural Sciences
Programme group Clinical Psychology
Visiting address
  • Nieuwe Achtergracht 129
Postal address
  • Postbus 15933
    1001 NK Amsterdam
Contact details
  • Publications

    2026

    • Cuijpers, P., Harrer, M., Miguel, C., Donker, T., Keshen, A., Karyotaki, E., & Linardon, J. (2026). Delivery formats of cognitive behavior therapy in adults with eating disorders: a network meta-analysis. Cognitive Behaviour Therapy, 55(2), 292-304. https://doi.org/10.1080/16506073.2025.2495950
    • Cuijpers, P., Harrer, M., Miguel, C., Karyotaki, E., & Papola, D. (2026). Does baseline severity interact with the effects of psychotherapy for depression? A meta-analytic review. Journal of Affective Disorders, 399, Article 121106. Advance online publication. https://doi.org/10.1016/j.jad.2025.121106 [details]
    • Pereira Ribeiro, J., Stoffers-Winterling, J., Jørgensen, M. S., Juul, S., Matbouriahi, M., Fisher, D., van Ballegooijen, W., Kongerslev, M., Simonsen, E., Karyotaki, E., Cuijpers, P., Bateman, A., Klein, J. P., Amianto, F., Fonagy, P., Dixon-Gordon, K., Chapman, A. L., Thomaes, K., Jacob, G. A., ... Storebø, O. J. (2026). Treatment modifiers of interpersonal functioning in psychotherapy for people with borderline personality disorder: Systematic review with meta-analyses of individual participant data. Clinical Psychology Review, 124, Article 102707. https://doi.org/10.1016/j.cpr.2026.102707

    2025

    • Ciharova, M., Amarti, K., van Breda, W., Gevonden, M. J., Ghassemi, S., Kleiboer, A., Vinkers, C. H., Sep, M. S. C., Trofimova, S., Cooper, A. C., Peng, X., Schulte, M., Karyotaki, E., Cuijpers, P., & Riper, H. (2025). Machine-learning detection of stress severity expressed on a continuous scale using acoustic, verbal, visual, and physiological data: lessons learned. Frontiers in Psychiatry, 16, Article 1548287. https://doi.org/10.3389/fpsyt.2025.1548287 [details]
    • Cuijpers, P., Harrer, M., Miguel, C., Ciharova, M., Papola, D., Basic, D., Botella, C., Cristea, I., De Ponti, N., Donker, T., Driessen, E., Franco, P., Gómez-Gómez, I., Hamblen, J., Jiménez-Orenga, N., Karyotaki, E., Keshen, A., Linardon, J., Motrico, E., ... Furukawa, T. A. (2025). Cognitive Behavior Therapy for Mental Disorders in Adults: A Unified Series of Meta-Analyses. JAMA Psychiatry, 82(6), 563-571. https://doi.org/10.1001/jamapsychiatry.2025.0482
    • Cuijpers, P., Harrer, M., Miguel, C., Keshen, A., Karyotaki, E., & Linardon, J. (2025). Absolute and relative outcomes of cognitive behavior therapy for eating disorders in adults: a meta-analysis. Eating Disorders, 33(6), 783-804. https://doi.org/10.1080/10640266.2024.2421057
    • Harrer, M., Metapsy consortium, Miguel, C., Tong, L., Kuper, P., Sprenger, A. A., Furukawa, Y., Wang, Y., van Ballegooijen, W., Ciharova, M., Panagiotopoulou, O. M., Cristea, I., Hamblen, J. L., Schnurr, P. P., Riper, H., Sijbrandij, M., Karyotaki, E., van Straten, A., Furukawa, T. A., ... Cuijpers, P. (2025). Effectiveness of digital interventions for eight mental disorders: A meta-analytic synthesis. Internet Interventions, 41, Article 100860. https://doi.org/10.1016/j.invent.2025.100860
    • Harrer, M., Miguel, C., Luo, Y., Ostinelli, E. G., Karyotaki, E., Leucht, S., Furukawa, T. A., & Cuijpers, P. (2025). Standardized effect sizes are far from “Standardized”: A primer and empirical illustration in depression psychotherapy meta-analyses. PLOS Mental Health, 2(7 July), Article e0000347. https://doi.org/10.1371/journal.pmen.0000347
    • Harrer, M., Miguel, C., van Ballegooijen, W., Ciharova, M., Plessen, C. Y., Kuper, P., Sprenger, A. A., Buntrock, C., Papola, D., Cristea, I. A., de Ponti, N., Bašić, Đ., Pauley, D., Driessen, E., Quero, S., Grimaldos, J., Buendía, S. F., Botella, C., Hamblen, J. L., ... Cuijpers, P. (2025). Effectiveness of Psychotherapy: Synthesis of a “Meta-Analytic Research Domain” Across World Regions and 12 Mental Health Problems. Psychological Bulletin, 151(5), 600-667. https://doi.org/10.1037/bul0000465
    • Harrer, M., Sprenger, A. A., Illing, S., Adriaanse, M. C., Albert, S. M., Allart, E., Almeida, O. P., Basanovic, J., Van Bastelaar, K. M. P., Batterham, P. J., Baumeister, H., Berger, T., Blanco, V., Bø, R., Casten, R. J., Chan, D., Christensen, H., Ciharova, M., Cook, L., ... Ebert, D. D. (2025). Psychological intervention in individuals with subthreshold depression: individual participant data meta-analysis of treatment effects and moderators. British Journal of Psychiatry. Advance online publication. https://doi.org/10.1192/bjp.2025.56
    • Homiar, A., Thomas, J., Ostinelli, E. G., Kennett, J., Friedrich, C., Cuijpers, P., Harrer, M., Leucht, S., Miguel, C., Rodolico, A., Kataoka, Y., Takayama, T., Yoshimura, K., So, R., Tsujimoto, Y., Yamagishi, Y., Takagi, S., Sakata, M., Bašić, Đ., ... Cipriani, A. (2025). Development and evaluation of prompts for a large language model to screen titles and abstracts in a living systematic review. BMJ Mental Health, 28(1), Article e301762. https://doi.org/10.1136/bmjment-2025-301762 [details]
    • Kataoka, Y., Takayama, T., Yoshimura, K., So, R., Tsujimoto, Y., Yamagishi, Y., Takagi, S., Furukawa, Y., Sakata, M., Bašić, Đ., Cipriani, A., Cuijpers, P., Karyotaki, E., Harrer, M., Leucht, S., Homiar, A., Ostinelli, E. G., Miguel, C., Rodolico, A., & Furukawa, T. A. (2025). Automating the data extraction process for systematic reviews using GPT-4o and o3. Research synthesis methods. https://doi.org/10.1017/rsm.2025.10030
    • Kuper, P., Miguel, C., Cuijpers, P., Apfelbacher, C., Buntrock, C., Karyotaki, E., Sprenger, A. A., & Harrer, M. (2025). Sample size and geographical region predict effect heterogeneity in psychotherapy research for depression: a meta-epidemiological study. Journal of Clinical Epidemiology, 183, Article 111779. https://doi.org/10.1016/j.jclinepi.2025.111779
    • Lin, T., Cohen, Z. D., Stefan, S., Șoflău, R., Fodor, L. A., Georgescu, R., Bruijniks, S. J. E., Lemmens, L., Bagby, M., Quilty, L., Ekeblad, A., Holmqvist, R., Evans, J., O’Mahen, H. A., Johnson, J. E., Zlotnick, C., Hilpert, P., Carter, J., McBride, C., ... Driessen, E. (2025). Efficacy and moderators of cognitive behavioural therapy versus interpersonal psychotherapy for adult depression: study protocol of a systematic review and individual participant data meta-analysis. BMJ Open, 15(12), Article e111686. https://doi.org/10.1136/bmjopen-2025-111686
    • Malhi, G. S., Adlington, K., Al-Diwani, A., Ali, S., Arya, R., Baldwin, D. S., Batley, P., Bell, E., Berrios, G., Beveridge, A., Bhat, M., Bhugra, D., Biswas, A., Byford, S., Campbell, C., Cass, H., Chadda, R. K., Chamberlain, S. R., Chevance, A., ... Fernandez-Egea, E. (2025). The value of mental science: we publish what matters. British Journal of Psychiatry, 227(1), 429-433. https://doi.org/10.1192/bjp.2025.118
    • Miguel, C., Harrer, M., Karyotaki, E., Plessen, C. Y., Ciharova, M., Furukawa, T. A., Cristea, I. A., & Cuijpers, P. (2025). Self-reports vs clinician ratings of efficacies of psychotherapies for depression: A meta-analysis of randomized trials. Epidemiology and Psychiatric Sciences, 34, Article e15. https://doi.org/10.1017/S2045796025000095
    • Pereira Ribeiro, J., Stoffers-Winterling, J., Jørgensen, M. S., Juul, S., Matbouriahi, M., Fisher, D., van Ballegooijen, W., Kongerslev, M. T., Simonsen, E., Karyotaki, E., Cuijpers, P., Bateman, A., Klein, J. P., Amianto, F., Fonagy, P., Porter, R., Dixon-Gordon, K., Chapman, A. L., Thomaes, K., ... Storebø, O. J. (2025). Treatment Moderators of Symptom Severity in Psychotherapy for People with Borderline Personality Disorder: Systematic Review with Meta-Analyses of Individual Participant Data. Psychotherapy and Psychosomatics, Article 102707. Advance online publication. https://doi.org/10.1159/000548417
    • Plessen, C. Y., Panagiotopoulou, O. M., Tong, L., Cuijpers, P., & Karyotaki, E. (2025). Digital mental health interventions for the treatment of depression: A multiverse meta-analysis. Journal of Affective Disorders, 369, 1031-1044. https://doi.org/10.1016/j.jad.2024.10.018
    • Ramos, G., Karyotaki, E., Mohr, D. C., & Schueller, S. M. (2025). Digital Mental Health Treatments for Depression. Psychiatric Clinics of North America. Advance online publication. https://doi.org/10.1016/j.psc.2025.08.023
    • Wright, S. L., Karyotaki, E., Sijbrandij, M., Cuijpers, P., Bisson, J. I., Papola, D., Witteveen, A. B., Back, S. E., Bichescu-Burian, D., Capezzani, L., Cloitre, M., Devilly, G. J., Elbert, T., Mello, M. F., Ford, J. D., Grasso, D., Gray, R., Haller, M., Hunt, N., ... Seedat, S. (2025). Efficacy of Cognitive Behavioral Therapies With a Trauma Focus for Posttraumatic Stress Disorder: An Individual Participant Data Meta-Analysis. Journal of consulting and clinical psychology, 93(6), 401-426. https://doi.org/10.1037/ccp0000942
    • Wright, S. L., Kessler, A., Sijbrandij, M., Karyotaki, E., Cuijpers, P., Bisson, J., Brady, K., Dowd, S. M., Dunlop, B. W., Pollack, M. H., Rothbaum, B. O., & Seedat, S. (2025). Exploring study dropout in drug trials for adults with PTSD: insights from a conventional and individual participant data meta-analysis. European Journal of Psychotraumatology, 16(1), Article 2504839. https://doi.org/10.1080/20008066.2025.2504839

    2024

    • Koelen, J., Klein, A., Wolters, N., Bol, E., De Koning, L., Roetink, S., Van Blom, J., Boutin, B., Schaaf, J., Grasman, R., Van der Heijde, C. M., Salemink, E., Riper, H., Karyotaki, E., Cuijpers, P., Schneider, S., Rapee, R., Vonk, P., & Wiers, R. (2024). Web-Based, Human-Guided, or Computer-Guided Transdiagnostic Cognitive Behavioral Therapy in University Students With Anxiety and Depression: Randomized Controlled Trial. JMIR Mental Health, 11, Article e50503. https://doi.org/10.2196/50503 [details]

    2025

    • Etzelmueller, A., Vis, C., Karyotaki, E., Baumeister, H., Titov, N., Berking, M., Cuijpers, P., Riper, H., & Ebert, D. D. (2025). Correction: Effects of Internet-Based Cognitive Behavioral Therapy in Routine Care for Adults in Treatment for Depression and Anxiety: Systematic Review and Meta-Analysis (Journal of Medical Internet Research (2020) 22:8 (e18100) DOI: 10.2196/18100). Journal of Medical Internet Research, 27, Article e69127. https://doi.org/10.2196/69127
    • Miguel, C., Cristea, I. A., & Karyotaki, E. (2025). From clinical trials to real-world effectiveness: evaluating guided iCBT for depression in routine care. The Lancet Psychiatry, 12(3), 163-165. https://doi.org/10.1016/S2215-0366(25)00030-6
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