A.C. (Anne) Trutti
Faculty of Social and Behavioural Sciences
Programme group Brain and Cognition
Area of expertise: Cognitive neuroscience, dopamine system, midbrain, MRI, fMRI
Visiting address
- Nieuwe Achtergracht 129
- Room number: 0.07
Postal address
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Postbus 15915
1001 NK Amsterdam
Contact details
Social media
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Profile
In my research, I utilize high-resolution neuroimaging techniques, such as 7 Tesla (7T) MRI, to study the structure and function of the dopaminergic midbrain, with a particular focus on the human ventral tegmental area (VTA). Combining functional MRI (fMRI) with structural imaging methods, including quantitative MRI and diffusion-based techniques like probabilistic tractography, I investigate the anatomy and functional organization of the dopaminergic subcortex.
A central aim of my research is to advance our understanding of the subcortex as a whole, with a specific focus on the dopaminergic midbrain and the striatum. I seek to test whether cognitive functions traditionally localized in subcortical regions through animal studies can be accurately mapped in the human brain.
In my current postdoctoral projects, I employ a range of fMRI analysis methods and joint modeling of behavioral and neural data to explore the subcortex's involvement in cognitive processes such as working memory, risk-taking, reward, and learning.
Other links
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Research
Research methods
- Quantitative MRI
- Functional MRI (fMRI)
- Diffusion MRI and probabilistic tractography
- Midbrain
- Dopamine
- Ventral tegmental area (VTA)
- Substantia nigra (SN)
- Striatum
- Working memory
- Reinforcement learning
- Cognitive control
Current research projects
- Investigating working memory updating processes of the subcortex – using 7T fMRI and joint modelling of behavioral and functional MRI data
- Exploring functional subdivisions of the dopaminergic midbrain – using 7T resting-state and task-based data
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Teaching
Courses
- Cognitive AI and NeuroImaging
- NeuroImaging: Bold-MRI
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Publications
2023
Isherwood, S. J. S., Bazin, P., Miletić, S., Stevenson, N. R., Trutti, A. C., Tse, D. H. Y., Heathcote, A., Matzke, D., Innes, R. J., Habli, S., Sokołowski, D. R., Alkemade, A., Håberg, A. K., & Forstmann, B. U. (2023). Investigating Intra-Individual Networks of Response Inhibition and Interference Resolution using 7T MRI. NeuroImage, 271, Article 119988. https://doi.org/10.1016/j.neuroimage.2023.119988 [details]
2022
- Alkemade, A., Mulder, M. J., Trutti, A. C., & Forstmann, B. U. (2022). Manual delineation approaches for direct imaging of the subcortex. Brain Structure and Function, 227(1), 219-297. https://doi.org/10.1007/s00429-021-02400-x [details]
- Keuken, M. C., Liebrand, L. C., Bazin, P.-L., Alkemade, A., van Berendonk, N., Groot, J. M., Isherwood, S. J. S., Kemp, S., Lute, N., Mulder, M. J., Trutti, A. C., Caan, M. W. A., & Forstmann, B. U. (2022). A high-resolution multi-shell 3T diffusion magnetic resonance imaging dataset as part of the Amsterdam Ultra-high field adult lifespan database (AHEAD). Data in Brief, 42, Article 108086. https://doi.org/10.1016/j.dib.2022.108086 [details]
2021
- Boag, R. J., Stevenson, N., van Dooren, R., Trutti, A. C., Sjoerds, Z., & Forstmann, B. U. (2021). Cognitive control of working memory: A model-based approach. Brain Sciences, 11(6), Article 721. https://doi.org/10.3390/brainsci11060721 [details]
- Miletić, S., Boag, R. J., Trutti, A. C., Stevenson, N., Forstmann, B. U., & Heathcote, A. (2021). A new model of decision processing in instrumental learning tasks. eLife, 10, Article e63055. https://doi.org/10.7554/eLife.63055 [details]
- Trutti, A. C., Fontanesi, L., Mulder, M. J., Bazin, P.-L., Hommel, B., & Forstmann, B. U. (2021). A probabilistic atlas of the human ventral tegmental area (VTA) based on 7 Tesla MRI data. Brain Structure and Function, 226(4), 1155-1167. https://doi.org/10.1007/s00429-021-02231-w [details]
- Trutti, A. C., Verschooren, S., Forstmann, B. U., & Boag, R. J. (2021). Understanding subprocesses of working memory through the lens of model-based cognitive neuroscience. Current Opinion in Behavioral Sciences, 38, 57-65. https://doi.org/10.1016/j.cobeha.2020.10.002 [details]
2019
- Isaacs, B. R., Trutti, A. C., Pelzer, E., Tittgemeyer, M., Temel, Y., Forstmann, B. U., & Keuken, M. C. (2019). Cortico-basal white matter alterations occurring in Parkinson's disease. PLoS ONE, 14(8), Article e0214343. https://doi.org/10.1371/journal.pone.0214343 [details]
- Trutti, A. C., Mulder, M. J., Hommel, B., & Forstmann, B. U. (2019). Functional neuroanatomical review of the ventral tegmental area. NeuroImage, 191, 258-268. https://doi.org/10.1016/j.neuroimage.2019.01.062 [details]
2017
- Keuken, M. C., Bazin, P.-L., Backhouse, K., Beekhuizen, S., Himmer, L., Kandola, A., Lafeber, J. J., Prochazkova, L., Trutti, A., Schäfer, A., Turner, R., & Forstmann, B. U. (2017). Effects of aging on T1, T∗2, and QSM MRI values in the subcortex. Brain Structure and Function, 222(6), 2487-2505. https://doi.org/10.1007/s00429-016-1352-4 [details]
2016
- de Hollander, G., Labruna, L., Sellaro, R., Trutti, A., Colzato, L. S., Ratcliff, R., Ivry, R. B., & Forstmann, B. U. (2016). Transcranial direct current stimulation does not influence the speed-accuracy tradeoff in perceptual decision-making: Evidence from three independent studies. Journal of Cognitive Neuroscience, 28(9), 1283-1294. https://doi.org/10.1162/jocn_a_00967 [details]
2023
- Isherwood, S., Bazin, P., Miletić, S., Stevenson, N., Trutti, A., H. Y. Tse, D., Heathcote, A., Matzke, D., Habli, S., Sokołowski, D. R., Alkemade, A., Håberg, A., Forstmann, B. & Innes, R. (8-6-2023). Investigating Intra-Individual Networks of Response Inhibition and Interference Resolution using 7T MRI data. Universiteit van Amsterdam. https://doi.org/10.21942/uva.22240393.v1
2021
- Keuken, M., Liebrand, L., Bazin, P., Alkemade, A., van Berendonk, N., Groot, J., Isherwood, S., Kemp, S., Lute, N., Mulder, M., Trutti, A., Caan, M. W. A. & Forstmann, B. (28-10-2021). A high-resolution multi-shell 3T diffusion magnetic resonance imaging dataset as part of the Amsterdam Ultra-high field adult lifespan database (AHEAD) - dataset. Universiteit van Amsterdam. https://doi.org/10.21942/uva.16884703.v1
- Alkemade, J. M., Mulder, M. J., Trutti, A. C. & Forstmann, B. U. (16-3-2021). Manual Delineation approaches for direct imaging of the subcortex. Universiteit van Amsterdam. https://doi.org/10.21942/uva.14216504.v2
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Ancillary activities
No ancillary activities
Isherwood, S. J. S., Bazin, P., Miletić, S., Stevenson, N. R., Trutti, A. C., Tse, D. H. Y., Heathcote, A., Matzke, D., Innes, R. J., Habli, S., Sokołowski, D. R., Alkemade, A., Håberg, A. K., & Forstmann, B. U. (2023). Investigating Intra-Individual Networks of Response Inhibition and Interference Resolution using 7T MRI. NeuroImage, 271, Article 119988.