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Rita Vuyk Lectures

Developmental Psychology

Since January 2009 the department of Developmental Psychology has been organizing the "Rita Vuyk Lectures".

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About

These lectures are in honour of prof.dr. Margueritha Vuyk. She was the first full professor in Developmental Psychology at the University of Amsterdam. See the Album Academicum of the University of Amsterdam for more information.

Album Academicum of the University of Amsterdam

These monthly lectures will have a diverse character with a wide range of eminent speakers and could be of interest to both students and employees from all departments. Here, the dates, speakers and topics for the Rita Vuyk lectures are listed.

For upcoming lectures see below. For a full overview see the Archive.

Tuesday 16th of April, 16.00-17.00 in REC E0.14. Dr. Jeffrey Glennon, Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behavior, Nijmegen

Inattention is causal to aggression: evidence from preclinical, population and clinical studies

Overt aggression in oppositionalcur with and without comorbid attention-deficit hyperactivity disorder (ADHD). The substrates of aggression are complex but are often prescribed to failures in self-control, empathy, morality and reasoning. Underlying these constructs are cognitive and emotional constructs including perception processing, sensory integration of (social) information, reward sensitivity and the ability to learn. In particular, the inability to learn from punishment is a hallmark of callous unemotional traits which when present renders the clinical management of these cases to be more problematic. Here we Bayesian machine learning, phenotypic data sets in two ADHD (1 childhood (ADHD200) and 1 adolescent (NeuroIMAGE) cohorts and controls; n=245 and 305 respectively. Using the same approach, we confirm this in the adolescent ALSPAC population cohort (N=5987) which suggests that gender influences inattention which in turn has a causal relationship with aggression. In addition, data from the ACTION consortium within the Dutch Twin register confirms a correlation between inattention and aggression in adolescents in a sample of 11,500 twins. In rodents, inattention is seen in aggressive mice (5-choice serial reaction time task & continuous performance task (CPT) in BALB/cJ mice.
Interestingly, while pharmacological interventions are secondary interventions in CD management, the dopamine / noradrenaline reuptake blocker methylphenidate (used to treat ADHD) improves the false alarm rate probability in the CPT in BALB/cJ at the same dose which decreases aggression.
Within the MATRICS consortium, sustained inattention is present in ODD/CD cases (n=211) in the rapid visual processing task in the CANTAB independent of ADHD diagnosis. Taken together, we demonstrate that inattention may be an important mechanism underlying aggression and its remediation by methylphenidate. This may involve improvement of error detection / sustained attention to social cues enabling improved social cognition which acts to reduce antisocial behaviour.

This lecture is hosted by Reinout Wiers